The Life of Merlin

The Life of Merlin

The Life of Merlin


American Klezmer

American Klezmer

American Klezmer

Investigates American klezmer music: its roots, evolution and the revival that began in the 1970s.

Cancer Genome and Tumor Microenvironment

Cancer Genome and Tumor Microenvironment

Cancer Genome and Tumor Microenvironment

Oncogenes and tumor suppressor genes had been traditionally studied in the context of cell proliferation, differentiation, senescence, and survival, four relatively cell-autonomous processes. Consequently, in the late ’80s-early ’90s, neoplastic growth was described largely as an imbalance between net cell accumulation and loss, brought about through mutations in cancer genes. In the last ten years, a more holistic understanding of cancer has slowly emerged, stressing the importance of interactions between neoplastic and various stromal components: extracellular matrix, basement membranes, fibroblasts, endothelial cells of blood and lymphatic vessels, tumor-infiltrating lymphocytes, etc. The commonly held view is that changes in tumor microenvironment are “soft-wired”, i.e., epigenetic in nature and often reversible. Yet, there exists a large body of evidence suggesting that well-known mutations in cancer genes profoundly affect tumor milieu. In fact, these non-cell-autonomous changes might be one of the primary reasons such mutations are preserved in late-stage tumors.

2009 Minutes of the Cumberland Presbyterian Church

2009 Minutes of the Cumberland Presbyterian Church

2009 Minutes of the Cumberland Presbyterian Church

Annual minutes of the meeting of the Cumberland Presbyterian General Assembly for 2009.

Merlin

Merlin

Merlin

Stephen Knight traces the myth of Merlin from to the early Welsh figure of Myrddin, through centuries of literature and art, and to contemporary examples of literature, film, and television.

Tampa Bay Magazine

Tampa Bay Magazine

Tampa Bay Magazine

Tampa Bay Magazine is the area's lifestyle magazine. For over 25 years it has been featuring the places, people and pleasures of Tampa Bay Florida, that includes Tampa, Clearwater and St. Petersburg. You won't know Tampa Bay until you read Tampa Bay Magazine.